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1.2. Pediatrics

Select ACE inhibitors are FDA-approved for use to manage hypertension in pediatric patients. Maximum recommended ACE inhibitor doses for pediatric patients are summarized in Table 3. Dosages exceeding these recommendations will be reviewed.

Table 3.  Pediatric Maximum Recommended Dosages for ACE inhibitors in Hypertension [1-4,6-10]
DrugPatient CharacteristicsMaximum Daily Dosage
benazepril6 to 17 years of age  0.6 mg/kg/day up to 40 mg/day
enalapril1 month of age to 17 years of age0.58 mg/kg/day up to 40 mg/day
fosinopril6 to 17 years of age (greater than 50 kg) 40 mg daily
lisinopril6 to 17 years of age0.6 mg/kg/day up to 40 mg/day