Table 9: Pediatric Maximum Recommended Antidepressant Drug Dosages (Monotherapy)– Monoamine Oxidase Inhibitors

Treatment Indication Drug Name Available Dosage Strengths Literature Based Maximum Dosage FDA Approved Maximum Recommended Dosage
MDD isocarboxazid (Marplan®) 10 mg tablets Not reviewed
  • Greater than or equal to 16 years of age:  
    • 60 mg/day
MDD selegiline (EMSAM®) transdermal patch 6 mg/ 24 hours, 9 mg/ 24 hours, 12 mg/ 24 hours transdermal patch Age ≥ 12 years: 12 mg per 24 hours Not approved for pediatric use

Legend:

  • MDD = major depressive disorder