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3. Duplicative Therapy

Concurrent administration of nitazoxanide with other approved antibiotic therapies for cryptosporidiosis and giardiasis (i.e., paromomycin, metronidazole, tinidazole, paromomycin + azithromycin) is not recommended as these combinations do not provide additional therapeutic benefit and may result in enhanced adverse events. Patient profiles containing adjunctive prescriptions for nitazoxanide and additional cryptosporidiosis or giardiasis therapy will be reviewed.