1.1. Adults

Adult dosage recommendations for LTRAs are summarized in Table 1. Patient profiles containing dosages not conforming to these recommendations will be reviewed.

Table 1. LTRA Adult Dosage Recommendations^1-4

Drug Name	Dosage Form/Strength	Treatment Indication	Maximum Recommended Dosage
montelukast (Singulair®, generics)	10 mg tablets, 4 mg, 5 mg chewable tablets, 4 mg oral granule packets	asthma	10 mg once daily in the evening
		prophylaxis, exercise-induced bronchoconstriction	10 mg as a single dose, at least 2 hours before exercise; dose should not be repeated within 24 hours of previous dose
		perennial and/or seasonal allergic rhinitis	10 mg daily
zafirlukast (Accolate®, generics)	10 mg, 20 mg tablets	asthma	20 mg twice daily