2. Duration of Therapy

GLP-1 agonists are indicated for the management of type 2 diabetes mellitus and may be continued indefinitely, as control of blood glucose is a chronic, lifelong process. There is no basis for limiting the duration of treatment for GLP-1 agonists in patients using this medication for chronic weight management if it remains beneficial for weight loss and is not causing intolerable side effects¹⁶.16