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1. Dosage

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Nonselective oral and rectal NSAIDs are FDA-approved for use in rheumatoid arthritis/juvenile rheumatoid arthritis (JRA), osteoarthritis, ankylosing spondylitis, pain management, dysmenorrhea, fever, migraines and cluster headaches. JRA is now also known as juvenile idiopathic arthritis (JIA) or juvenile arthritis (JA). Diclofenac, ibuprofen, and naproxen are also available as combination therapy with gastric acid suppressants to minimize the risk of NSAID-associated gastric ulcer development1-39.