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1.1. Adults

Dosage recommendations for available calcineurin inhibitors are summarized in Table 1.

Table 1. Recommended Adult Dosages for Topical Calcineurin Inhibitors1-3
Drug NameDosage StrengthRecommended Dose/Directions
pimecrolimus (Elidel, generics) cream
  • 1% - 30 g, 60g, 100 g tube
apply thin layer of cream to affected area twice daily until symptoms resolve; use should be confined only to areas affected by atopic dermatitis; should not be used with occlusive dressings
tacrolimus (Protopic, generics) ointment
  • 0.03% - 30 g, 60 g, 100 g tube
  • 0.1% - 30 g, 60 g, 100 g tube
apply thin layer of 0.03% or 0.1% ointment to affected area twice daily, rubbing in completely, and continue until symptoms resolve; use should be confined only to areas affected by atopic dermatitis; should not be used with occlusive dressings

Patient profiles documenting prescriptions for greater than the equivalent of one 60 g tube of pimecrolimus cream or tacrolimus ointment per 30-day time period will be reviewed.