2. Duration of Therapy

The maximum treatment duration for aprepitant is three days per chemotherapy cycle for moderately or highly emetogenic chemotherapy regimens. The maximum treatment duration for rolapitant and netupitant/palonosetron is one day for each chemotherapy cycle. Chemotherapy regimens are administered for one to several days within a 30-day time period and repeated in cycles. The number of cycles varies based on the type of cancer being treated. Unless otherwise specified, aprepitant treatment regimens continuing for greater than three days per chemotherapy cycle and rolapitant and netupitant/palonosetron treatment regimens continuing for longer than one day per chemotherapy cycle will be reviewed for appropriateness of use.