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1. Dosage

HHSC does not support low-dose quetiapine use as non-FDA-approved sleep aid monotherapy. Data included in these criteria address available studies evaluating low-dose quetiapine in insomnia, the limits of these studies, as well as risks associated with quetiapine use for this indication.  Additionally, evidence-based use of lower quetiapine doses for FDA-approved and pediatric purposes is also discussed.